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Psychological Wellbeing
Mental Health · Strong evidence
Evidence
72
Impact
48
Positive psychological well-being, optimism and life satisfaction as protective factors for physical health.
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9 studies reviewed · 5 meta-analyses
Score history
Research summary
- Two independent meta-analyses link dispositional optimism to lower cardiovascular events and all-cause mortality, and a broader synthesis found psychological well-being predicts all-cause mortality independently of the absence of distress — suggesting wellbeing is not just the inverse of mental illness.
- Real cohort studies reinforce this: gratitude was associated with lower mortality among older US female nurses, and optimism was linked to greater longevity in a racially diverse cohort of women.
- A meta-analytic review specifically connects positive well-being to better cardiovascular health, and positive emotional states are associated with better cancer survival in meta-analysis.
- Nearly all of this evidence is observational rather than from trials that raise wellbeing and then measure mortality, so causation remains inferred; the associations are nonetheless consistent across multiple independent cohorts and outcomes.
Mood & StressLongevity
Studies9 considered · latest 2026
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