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Magnesium

Supplements · Moderate evidence

Evidence

62

Impact

38

Magnesium's most consistent evidence is for modestly lowering blood pressure and reducing type 2 diabetes risk.

Studies
10
RCTs
0
Meta-analyses
10

Research summary

  • Multiple independent meta-analyses of randomized trials, spanning from 2002 to 2025, consistently find magnesium supplementation produces a small but real reduction in blood pressure, with effects present across general and diabetic populations.
  • On the dietary side, several dose-response meta-analyses of prospective cohorts link higher magnesium intake to lower risk of type 2 diabetes, with a dedicated dose-response analysis also linking intake to lower cardiovascular disease and all-cause mortality risk.
  • For two commonly marketed uses — muscle cramps and sleep — the evidence is weaker: a Cochrane review found insufficient evidence that magnesium meaningfully reduces skeletal muscle cramps, and a meta-analysis specifically in older adults found only modest support for improving insomnia.
  • Overall, magnesium's blood-pressure and diabetes-risk associations are its best-supported effects, while cramps and sleep claims rest on thinner evidence.
Cardiovascular HealthMetabolic Health
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