Is Coenzyme Q10 good for cardiovascular health?

The evidence points that way, though it's not yet conclusive. Meta-analyses spanning from 1997 through a 2014 Cochrane review find CoQ10 supplementation can modestly improve symptoms and some outcomes in heart failure, though a 2022 health-technology assessment concluded the evidence is not yet strong enough to firmly establish cost-effective clinical benefit for reduced-ejection-fraction heart failure specifically. That's reflected in an evidence score of 58/100 for its role in cardiovascular health, drawn from 8 studies, with an estimated impact on longevity rated limited (30/100).