Does Vitamin B12 actually make a difference, or is it overhyped?

B12 deficiency is common enough in older adults to warrant real clinical attention, and a systematic review documents meaningful rates of subnormal B12 and associated anaemia in this group. Weighing the data: Vitamin B12 looks an early-stage, lower-priority area for now — the evidence is only moderate (40/100), and its estimated impact (20/100) is on the lower end too.