Does Creatine actually make a difference, or is it overhyped?

Creatine supplementation combined with resistance training consistently increases muscle strength and mass across multiple independent meta-analyses, including specifically in older adults and postmenopausal women, and improves upper-body and lower-body strength and power. Weighing the data: Creatine looks well-supported and consequential — the evidence is rated strong (88/100) and its estimated impact on longevity is also rated highly (68/100), making it one of the more solidly-backed choices on Vitaebase.