Legume Consumption and Risk of All-Cause and Cause-Specific Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies.

Zargarzadeh N, Mousavi SM, Santos HO, Aune D, Hasani-Ranjbar S, Larijani B, Esmaillzadeh A

Advances in nutrition (Bethesda, Md.) · January 1, 2023

There is an equivocal and inconsistent association between legume consumption and health outcomes and longevity. This study examined and quantified the potential dose-response relationship between legume consumption and all-cause and cause-specific mortality in the general population. Thirty-two cohorts involving 1,141,793 participants and 93,373 deaths from all causes were included. Higher intakes of legumes, compared with lower intakes, were associated with a reduced risk of mortality from all causes and stroke. There was no significant association for CVD, CHD, or cancer mortality. A 50 g/d increase in legume intake was associated with a 6% reduction in the risk of all-cause mortality. The certainty of evidence was judged from low to moderate. These results support dietary recommendations to increase the consumption of legumes.

PMID: 36811595 · DOI: 10.1016/j.advnut.2022.10.009