A dose-response meta-analysis on the relationship between daily tea intake and cardiovascular mortality based on the GRADE system.

Liu KF, Xue Y, Lu CY, Zhang XF, Yan SM, Kang J, Zhao J

Zhonghua xin xue guan bing za zhi · May 24, 2021

Objective: To explore the relationship between daily tea intake and cardiovascular disease (CVD) mortality. Methods: PubMed, EMbase, The Cochrane, Chinese Biomedical Literature Database, CNKI, and Wanfang Database were searched. A total of 21 cohort or case-control studies were included, including 1,304,978 subjects, among them 38,222 deaths from CVD were reported. Results: The dose-response meta-analysis showed that for every additional cup of tea intake per day, the mortality rate of CVD decreased by about 3% (95% CI 0.95-0.98, P<0.05). Compared with people who do not drink tea, people who drink 1 to 8 cups of tea a day have 8%-16% lower CVD mortality. The results of traditional meta-analysis showed that compared with people who do not drink tea, people who drink more than 1 cup of tea a day are associated with 14% lower CVD mortality rate (RR=0.86, 95% CI 0.81-0.91). The population who consumed green tea decreased CVD mortality by 15%, and the population of non-smokers decreased CVD mortality by 20% (all P<0.05). Conclusions: Daily tea consumption is related to reduced CVD mortality. It is therefore recommended to drink an appropriate amount of tea daily.

PMID: 34034384 · DOI: 10.3760/cma.j.cn112148-20200726-00592