Is Probiotics worth prioritizing?

Probiotics have some of the more consistently positive supplement evidence for a specific, common problem: multiple meta-analyses, including a landmark JAMA meta-analysis and two Cochrane reviews (one in children, one for C. Weighing that against the numbers, Probiotics is reasonable to include, though not a top priority — the evidence is rated strong (75/100), but its estimated effect on longevity is modest (48/100).