How strong is the evidence for Mindfulness?

The clearest and most rigorously tested application of structured mindfulness programs is relapse prevention in recovered depression: an individual-patient-data meta-analysis in JAMA Psychiatry, later corroborated by a network meta-analysis, found mindfulness-based cognitive therapy (MBCT) reduces depressive relapse about as effectively as maintenance antidepressants. That evidence is currently rated strong (78/100), built on 10 published studies, including 1 randomized controlled trial and 6 meta-analyses -- enough for real confidence in the effect.