How strong is the evidence for Indoor Air Quality?

Improving indoor air quality with portable HEPA filtration has a real but genuinely inconsistent randomized-trial evidence base, with cardiovascular benefits appearing in some trials and not others. That evidence is currently rated moderate (45/100), built on 5 published studies, including 5 randomized controlled trials -- a reasonable base, but not yet enough for full certainty.

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Indoor Air Quality

Moderate evidence

Evidence

Impact

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Key studies behind this answer

Bedroom Air Filtration and Home Blood Pressures of Older Adults Living in a Residential Facility.Randomized Controlled Trial · Journal of clinical hypertension (Greenwich, Conn.) · 2026 Reducing particulates in indoor air can improve the circulation and cardiorespiratory health of old people: A randomized, double-blind crossover trial of air filtration.Randomized Controlled Trial · The Science of the total environment · 2021 Reduced Fine Particulate Matter Air Pollution Exposures Using In-Home Portable Air Cleaners: PILOT RESULTS OF THE CARDIAC REHABILITATION AIR FILTER TRIAL (CRAFT).Randomized Controlled Trial · Journal of cardiopulmonary rehabilitation and prevention · 2020